Grapefruit juice, and other products based on the fruit, is a common cause of adverse reactions that occur in the interaction with dozens of drugs, including those for controlling cholesterol levels, anti-allergy drugs, antidepressants, drugs to lower blood pressure, pain medications, some antibiotics...
There are different assumptions regarding the negative
effects, which relate primarily to the inhibition of certain enzymes.
Inhibition of increases in blood concentrations of certain
drugs normally metabolized by these enzymes and leads to overdose and are
registered and fewer cases of reducing the concentration of drug in the blood,
and therefore less of their effectiveness.
